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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPTAN1 All Species: 27.58
Human Site: S423 Identified Species: 55.15
UniProt: Q13813 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13813 NP_001123910.1 2472 284539 S423 S F K S A D E S G Q A L L A A
Chimpanzee Pan troglodytes XP_001169918 2416 279460 T432 R F E S A R E T G Q D L L N A
Rhesus Macaque Macaca mulatta XP_001117106 2440 281752 T432 R F Q S A K E T G E D L L D A
Dog Lupus familis XP_537823 2573 295678 S519 S F K S A D E S G Q A L L A A
Cat Felis silvestris
Mouse Mus musculus P16546 2472 284579 S423 S F K S A D E S G Q A L L A A
Rat Rattus norvegicus P16086 2472 284619 S423 S F K S A D E S G Q A L L A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P07751 2477 285345 S423 S F R S A D E S G Q A L L A A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001091958 2480 284939 A423 S F K S T D E A G Q A L L N T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13395 2415 278284 S426 S F K L T T E S G Q K L L E R
Honey Bee Apis mellifera XP_623691 2418 278393 A427 S F D A T T L A G N K L L E K
Nematode Worm Caenorhab. elegans NP_508537 2427 281735 A440 S F N Q T A S A G Q K L V E M
Sea Urchin Strong. purpuratus XP_785949 2410 278516 E424 S F K Q C A E E G Q Q L L D E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 55.7 56.5 94.6 N.A. 98.4 98.5 N.A. N.A. 96.1 N.A. 90 N.A. 64.5 66.1 58.5 63
Protein Similarity: 100 72.9 73.5 95.6 N.A. 99.2 99.3 N.A. N.A. 98.3 N.A. 94.8 N.A. 78.9 79.6 75.1 77.5
P-Site Identity: 100 60 53.3 100 N.A. 100 100 N.A. N.A. 93.3 N.A. 73.3 N.A. 60 33.3 33.3 53.3
P-Site Similarity: 100 73.3 73.3 100 N.A. 100 100 N.A. N.A. 100 N.A. 80 N.A. 60 46.6 46.6 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 59 17 0 25 0 0 50 0 0 42 59 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 50 0 0 0 0 17 0 0 17 0 % D
% Glu: 0 0 9 0 0 0 84 9 0 9 0 0 0 25 9 % E
% Phe: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 59 0 0 9 0 0 0 0 25 0 0 0 9 % K
% Leu: 0 0 0 9 0 0 9 0 0 0 0 100 92 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 9 0 0 0 0 0 0 9 0 0 0 17 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 9 17 0 0 0 0 0 84 9 0 0 0 0 % Q
% Arg: 17 0 9 0 0 9 0 0 0 0 0 0 0 0 9 % R
% Ser: 84 0 0 67 0 0 9 50 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 34 17 0 17 0 0 0 0 0 0 9 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _